The OOCDB database is created and maintained by the team of Professor Gu Zhongze of Southeast University. Professor Gu Zhongze (Yangtze River Scholar of the Ministry of Education, National Outstanding Youth, American Academy of Medicine and Bioengineering Fellow) has long been engaged in organ chip research, and has successfully developed 14 important organ chips such as liver chip, tumor chip, heart chip, brain chip, etc., based on These organ chip models, the laboratory is generating a lot of first-hand important data resources. At the same time, the organ chip project was led by Professor Gu Zhongze of Southeast University. Relying on the academician team of Dave Weitz, Michael Shuler, Kam W Leong, Arun Majumdar, etc., the innovative team of the Ministry of Education based on the construction and application of organ chip based on biomaterials organized the organ chip research team. At the same time, the integrated resources declared the national meteorological project-the precise mesoscopic measurement of human organ chips.

Organ chip is a scientific technology with the main feature of manipulating fluids in micron-scale space. Organ chips have been regarded as a very important emerging scientific and technological platform and a strategic field of industrial transformation at the national level. The organ chip was named one of the world's "Top 10 Emerging Technologies" in 2016 by the World Economic Forum (Davos Forum). At present, the mainstream form of microfluidic chip refers to the integration or basic integration of basic operation units such as sample preparation, reaction, separation, detection, cell culture, sorting, and lysis in the fields of chemistry and biology. On a centimeter or smaller chip, a network of micro channels forms a controlled fluid throughout the system, a technology used to realize various functions of different laboratories in conventional chemistry, biology, materials, optics, etc. The basic characteristics and biggest advantages of the microfluidic chip laboratory are the flexible combination and scale integration of multiple unit technologies on a tiny platform that can be controlled overall. The human organ chip can provide a model similar to the human environment for medical, pharmaceutical and life science research, as well as data for alternative animals and clinical experiments for drug development and screening, disease model construction and other studies. The data generated by it is currently in the early stage of the "blowout" state. Therefore, it is also necessary to establish China National Organ Chip Science Data Center at the right time.

Organ on a Chip Database (OOCDB) is a unified platform (Science as a Service) that provides organ chip biological big data sharing and application services for scientific research communities. It is based on big data, artificial intelligence and Cloud computing technology provides data services specifically for organ chip data archiving, computational analysis, knowledge search, sharing services, and visualization. OOCDB currently integrates data from its own laboratory data, registered collaborator data, and published public data, including published academic literature, patents, and public database data. OOCDB organizes, archives, annotates, analyzes and visualizes these data, and finally forms: projects, tissues and organs, cell types, organ chip devices, technology, disease models, drugs and poisons, brain organs special library, online analysis More than 10 sub-databases and modules such as models and tools, visual display, standardization, and academic community communication. OOCDB searches and builds an index, and correlates these data with organ tissue and drug, poison and disease model research, so as to realize the traceability of the entire process of organ chip data from specific organization to project research to information data to achieve comprehensive data. More importantly, our database is updated in real time to complete the latest academic papers and related information updates, and to provide the latest progress in the field of organ chip research, research hotspot analysis, real-time online statistics in academic related fields, for global organ chips Researchers and experts in the fields of industry and government health medicine provide the most comprehensive, real-time and dynamic progress in the latest organ chip research. Our database provides data foundation and analysis tools for scientific research, industrial application, and standardization of organ chip technology.

OOCDB is based on its own data source of national organ chip database and data source of published literature, as well as external NCBI, EBI, OpenFDA, TogoWS, UniChem, DrugBank, ChEMBL, clinicaltrials.gov, ctti-clinicaltrials.org, NAMCS / NHAMCS, TOXNET, GTEx and other data sources, following INSDC, DataCite, GA4GH, GGBN, ACMG and other international standard alliance standards, have constructed coverage literature, research, tissues and organs, drugs, poisons, physiological models, disease models, providing data archiving, query retrieval, calculation, etc. Data sharing and application services.

Please refer to the following text to quote OOCDB:

OOCDB data archiving, data search, data calculation, scientific database and other external service data sources mainly come from NCBI, EBI, OpenFDA, TogoWS, UniChem, DrugBank, ChEMBL, clinicaltrials.gov, ctti-clinicaltrials.org, NAMCS / NHAMCS, TOXNET, Public data of GTEx and other databases. We sincerely thank these databases for providing us with rich biomedical data resources, and sincerely thank them for their contributions to the cause of biological data archiving and sharing. OOCDB has no special restrictions on the use of these public data resources. However, these data are subject to the terms and conditions of these external databases. Before using these external databases to disclose data, please review the specific terms and conditions of each database to be used to ensure compliance with all applicable regulations.

All public data and data services provided by OOCDB are free for users worldwide.